RNU6-640P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-640P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-640P data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RNU6-640P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-640P expression acts as an unfavorable survival marker, although some lineages such as STAD and PAAD show a favorable association.

COAD, STAD, and MESO are the cancer types where RNU6-640P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADOSTertileAll0.3950.655<.001132view →
STADOSMedianIII,IV0.5420.218<.001104view →
MESOOSTertileIII,IV0.2940.597<.00199view →
ACCDFSTertileAll0.1300.680<.00187view →
KIRPOSTertileIII,IV0.2270.731<.00148view →
LGGDFSTertileAll0.5590.758<.00136view →
PAADOSTertileII,III,IV0.7280.360.01824view →
BRCAOSTertileIII,IV0.9260.805.02624view →
UCSDFSTertileII,III,IV0.1750.472.02818view →
UVMDFSTertileIII,IV0.1420.715.0089view →
LUSCDFSTertileAll0.8000.449.0209view →
PCPGOSTertileAll0.6700.944.0419view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration