RNU6-638P

Across TCGA pan-cancer cohorts, RNU6-638P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RNU6-638P data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher RNU6-638P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-638P expression acts as an unfavorable survival marker, although some lineages such as READ and HNSC show a favorable association.

TGCT, READ, and HNSC are the cancer types where RNU6-638P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Tertile	III,IV	0.003	1.000	<.001	76	view →
READ	OS	Quartile	III,IV	0.725	0.320	.005	39	view →
HNSC	OS	Median	All	0.458	0.321	.002	38	view →
UCEC	DFS	Tertile	IV	0.756	0.292	.005	36	view →
BLCA	OS	Median	III,IV	0.447	0.304	.013	22	view →
KIRC	DFS	Tertile	IV	0.200	0.415	.010	21	view →
PCPG	DFS	Median	All	0.851	0.962	.001	21	view →
UCS	OS	Median	II,III,IV	0.638	0.271	.019	20	view →
BRCA	DFS	Quartile	III,IV	0.659	0.481	.016	14	view →
THYM	DFS	Tertile	All	1.000	0.716	.020	13	view →
STAD	OS	Median	All	0.725	0.604	.018	8	view →
KICH	DFS	Quartile	All	0.634	0.899	.015	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RNU6-638P–TGCT (OS)

Open the TGCT breakdown →