RNU6-634P

Across TCGA pan-cancer cohorts, RNU6-634P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-634P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU6-634P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-634P expression acts as an unfavorable survival marker, although some lineages such as GBM and KIRC show a favorable association.

HNSC, COAD, and UCEC are the cancer types where RNU6-634P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.169	0.674	<.001	126	view →
COAD	OS	Tertile	II,III,IV	0.185	0.792	<.001	42	view →
UCEC	OS	Tertile	All	0.409	0.679	.013	36	view →
THYM	DFS	Tertile	All	0.091	0.884	<.001	36	view →
MESO	DFS	Tertile	III,IV	0.078	0.376	.012	27	view →
SKCM	OS	Tertile	All	0.645	0.878	.010	12	view →
LUSC	OS	Tertile	II,III,IV	0.176	0.677	.047	9	view →
GBM	OS	Tertile	All	0.798	0.397	.043	6	view →
KIRC	DFS	Tertile	All	1.000	0.867	.048	6	view →
LGG	OS	Tertile	All	0.762	0.897	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNU6-634P–HNSC (OS)

Open the HNSC breakdown →