RNU6-62P

Across TCGA pan-cancer cohorts, RNU6-62P RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of RNU6-62P’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RNU6-62P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-62P is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and PRAD are the cancer types where RNU6-62P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-62P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	III,IV	−1.051	<.001	8	view →
LUSC	All	II,III,IV	−0.618	<.001	6	view →
PRAD	All	All	+1.090	<.001	2	view →
UCEC	All	All	−0.395	.008	2	view →
THCA	Female	All	−0.386	<.001	2	view →
BLCA	All	All	−0.306	.036	2	view →
KIRC	Male	III,IV	−0.497	.028	1	view →
CHOL	All	All	+0.408	.034	1	view →
LIHC	All	All	+0.128	.014	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

RNU6-62P–LUAD

Open the LUAD breakdown →