RNU6-625P

Across TCGA pan-cancer cohorts, RNU6-625P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-625P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-625P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-625P expression acts as an unfavorable survival marker, although some lineages such as LAML and BRCA show a favorable association.

MESO, ESCA, and BLCA are the cancer types where RNU6-625P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.077	0.580	<.001	90	view →
ESCA	OS	Tertile	All	0.382	1.000	<.001	70	view →
BLCA	DFS	Tertile	IV	0.168	0.485	.006	36	view →
COAD	OS	Tertile	II,III,IV	0.133	0.850	<.001	36	view →
UCEC	DFS	Tertile	All	0.115	0.651	.001	36	view →
SKCM	OS	Tertile	II,III,IV	0.104	0.321	.004	27	view →
LAML	DFS	Quartile	All	0.676	0.232	.003	26	view →
BRCA	OS	Tertile	III,IV	1.000	0.812	.015	24	view →
LUAD	OS	Tertile	III,IV	0.223	0.677	.006	24	view →
SARC	DFS	Tertile	All	0.259	0.525	.010	21	view →
KIRC	DFS	Tertile	All	0.323	0.638	.003	18	view →
LGG	OS	Tertile	All	0.808	0.397	.009	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

RNU6-625P–MESO (OS)

Open the MESO breakdown →