RNU6-622P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-622P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RNU6-622P data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher RNU6-622P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-622P expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

STAD, KICH, and KIRC are the cancer types where RNU6-622P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADDFSTertileIII,IV0.9450.536.00575view →
KICHDFSTertileAll0.1020.848.00439view →
KIRCDFSTertileIV0.1090.640<.00136view →
UCECOSTertileIII,IV0.3030.594.03218view →
KIRPOSTertileAll0.1870.708.00212view →
BLCADFSTertileIII,IV0.1590.572.0369view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration