RNU6-612P

Across TCGA pan-cancer cohorts, RNU6-612P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-612P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNU6-612P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-612P expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

KICH, PAAD, and UCEC are the cancer types where RNU6-612P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
PAAD	OS	Tertile	All	0.233	0.615	.010	72	view →
UCEC	DFS	Tertile	All	0.717	0.900	.001	66	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	27	view →
LIHC	OS	Tertile	All	0.144	0.688	.013	27	view →
SKCM	DFS	Tertile	II,III,IV	0.188	0.570	.041	18	view →
LGG	OS	Tertile	All	0.207	0.810	.010	18	view →
SARC	OS	Tertile	All	0.108	0.827	<.001	18	view →
LUAD	DFS	Tertile	All	0.206	0.767	.006	18	view →
LAML	DFS	Tertile	All	0.642	0.338	.039	12	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNU6-612P–KICH (DFS)

Open the KICH breakdown →