RNU6-607P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-607P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-607P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU6-607P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-607P expression acts as an unfavorable survival marker, although some lineages such as BRCA and ESCA show a favorable association.

SKCM, THCA, and UVM are the cancer types where RNU6-607P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMOSTertileAll0.5130.798<.00148view →
THCADFSTertileIV0.1260.805.00236view →
UVMOSTertileAll0.2200.917<.00136view →
KIRCDFSTertileIV0.1140.626<.00136view →
PRADOSTertileAll0.7700.990<.00136view →
BLCADFSTertileAll0.1210.594.00933view →
BRCADFSTertileIII,IV0.9010.452.02918view →
GBMDFSTertileAll0.0310.257<.00118view →
ACCOSTertileAll0.4740.830.03618view →
COADOSTertileAll0.2210.799.03218view →
PCPGDFSTertileAll0.1120.769.02118view →
ESCADFSTertileIII,IV0.7670.268.02815view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration