RNU6-600P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-600P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-600P data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RNU6-600P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-600P expression acts as an unfavorable survival marker.

LUSC, MESO, and DLBC are the cancer types where RNU6-600P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUSCOSTertileII,III,IV0.2660.635.00766view →
MESOOSTertileAll0.3230.558.01545view →
DLBCOSTertileIII,IV0.1540.735.01040view →
LIHCOSTertileIII,IV0.2700.732.02124view →
STADOSTertileII,III,IV0.4650.747<.00121view →
KIRCDFSTertileAll0.4280.642.04012view →
SKCMDFSTertileII,III,IV0.2180.685.0089view →
PCPGDFSTertileAll0.5970.831.0439view →
Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

Exploration