RNU6-599P

Across TCGA pan-cancer cohorts, RNU6-599P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-599P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-599P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-599P expression acts as an unfavorable survival marker.

KIRC, HNSC, and LUAD are the cancer types where RNU6-599P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.177	0.648	<.001	78	view →
HNSC	DFS	Tertile	All	0.163	0.696	.007	72	view →
LUAD	OS	Tertile	All	0.250	0.812	.002	45	view →
ACC	OS	Tertile	All	0.214	0.802	.002	45	view →
LGG	DFS	Tertile	All	0.118	0.832	<.001	18	view →
LUSC	OS	Tertile	All	0.323	0.677	.046	9	view →
STAD	DFS	Tertile	All	0.432	0.640	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RNU6-599P–KIRC (DFS)

Open the KIRC breakdown →