RNU6-597P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-597P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNU6-597P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RNU6-597P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-597P expression acts as an unfavorable survival marker, although some lineages such as STAD and HNSC show a favorable association.

THCA, KICH, and READ are the cancer types where RNU6-597P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCADFSTertileAll0.5030.836<.001120view →
KICHDFSTertileAll0.0810.904<.00190view →
READOSTertileAll0.1830.827<.00181view →
LUSCOSTertileIII,IV0.2000.579.01272view →
OVOSQuartileIII,IV0.7810.857.00324view →
SARCOSTertileAll0.1650.773<.00124view →
SKCMDFSTertileIV0.0400.454.02818view →
MESOOSTertileAll0.3070.556.03118view →
STADOSTertileIV0.5570.116.01716view →
THYMOSTertileAll0.4940.903.01112view →
LUADOSTertileIII,IV0.3140.683.0479view →
LIHCDFSTertileIII,IV0.0400.334<.0019view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

Exploration