Across TCGA pan-cancer cohorts, RNU6-595P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU6-595P’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where RNU6-595P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-595P is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

STAD, LUAD, and CHOL are the cancer types where RNU6-595P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-595P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	Male	All	+0.850	<.001	4	view →
LUAD	Female	III,IV	+0.893	.003	2	view →
CHOL	All	All	+0.757	.025	1	view →
KICH	All	All	−0.370	.022	1	view →
KIRC	All	All	+0.204	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RNU6-595P RNA expression & survival · all RNU6-595P data types