RNU6-561P

Across TCGA pan-cancer cohorts, RNU6-561P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-561P data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RNU6-561P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-561P expression acts as an unfavorable survival marker, although some lineages such as LGG and UCEC show a favorable association.

LUAD, PAAD, and STAD are the cancer types where RNU6-561P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	0.109	0.750	<.001	108	view →
PAAD	DFS	Tertile	All	0.079	0.484	<.001	36	view →
STAD	DFS	Tertile	All	0.438	0.723	.017	36	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
LIHC	OS	Tertile	All	0.049	0.787	<.001	36	view →
KIRC	DFS	Tertile	II,III,IV	0.160	0.663	.002	30	view →
BLCA	DFS	Tertile	All	0.159	0.625	.016	27	view →
READ	OS	Tertile	All	0.191	0.661	<.001	27	view →
KIRP	OS	Tertile	All	0.580	0.903	.006	27	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
LGG	OS	Tertile	All	0.987	0.884	.009	12	view →
PCPG	DFS	Tertile	All	0.434	0.828	.008	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

RNU6-561P–LUAD (OS)

Open the LUAD breakdown →