RNU6-55P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNU6-55P mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNU6-55P-associated genes across cancer lineages are ZBTB8OSP2, FXNP2, and TIGAR. Each is linked with RNU6-55P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU6-55P-to-partner and partner-to-RNU6-55P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-55P→partner) and Y-score (partner→RNU6-55P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECZBTB8OSP2 →+1.032+3.245.001.00931
UCECFXNP2 →+0.360+3.454<.001<.00131
UCECTIGAR →+0.845+3.210<.001.00931
UCECMIR7702 →+0.373+5.060<.001.00131
SKCMNMBR-AS1 →+0.236+5.513<.001.00431
SKCMLINC02283 →+0.169+6.469<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

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