Across TCGA pan-cancer cohorts, RNU6-556P RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated RNU6-556P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-556P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-556P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

KIRC, SKCM, and BLCA are the cancer types where RNU6-556P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	II,III,IV	0.167	0.520	.002	60	view →
SKCM	OS	Tertile	All	0.559	0.880	<.001	27	view →
BLCA	DFS	Tertile	All	0.196	0.627	.009	27	view →
ESCA	OS	Tertile	III,IV	0.828	0.361	.032	18	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNU6-556P tumor-vs-normal RNA expression · all RNU6-556P data types