RNU6-546P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-546P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RNU6-546P data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNU6-546P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-546P expression acts as an unfavorable survival marker.

UCEC, CESC, and LIHC are the cancer types where RNU6-546P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSTertileAll0.0950.679<.001108view →
CESCOSTertileAll0.1920.798<.00190view →
LIHCDFSTertileAll0.1130.545<.00154view →
THYMOSTertileAll0.1860.931<.00145view →
STADOSTertileIV0.0750.496.01324view →
LUADOSTertileAll0.3220.685.02418view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration