RNU6-543P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-543P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RNU6-543P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNU6-543P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-543P expression acts as an unfavorable survival marker.

KICH, BLCA, and STAD are the cancer types where RNU6-543P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KICHDFSTertileAll0.0810.904<.00190view →
BLCADFSTertileAll0.1000.626<.00154view →
STADOSTertileAll0.1060.538.01645view →
UCECOSTertileAll0.6980.929.00718view →
KIRPOSTertileAll0.1050.688.0329view →
HNSCOSTertileII,III,IV0.1320.400.0353view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration