RNU6-537P

Across TCGA pan-cancer cohorts, RNU6-537P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU6-537P data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher RNU6-537P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-537P expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

READ, BLCA, and LIHC are the cancer types where RNU6-537P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	All	0.296	0.828	<.001	72	view →
BLCA	OS	Tertile	III,IV	0.147	0.588	.001	36	view →
LIHC	OS	Tertile	All	0.240	0.713	<.001	27	view →
GBM	DFS	Tertile	All	0.048	0.257	.001	18	view →
DLBC	DFS	Tertile	III,IV	0.137	0.790	<.001	18	view →
KIRP	OS	Tertile	III,IV	0.268	0.808	.012	18	view →
LGG	OS	Tertile	All	0.789	0.912	.021	15	view →
THYM	OS	Tertile	All	0.381	0.879	.003	12	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
LAML	DFS	Quartile	All	0.447	0.264	.037	4	view →
ESCA	DFS	Quartile	All	0.360	0.517	.049	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RNU6-537P–READ (OS)

Open the READ breakdown →