RNU6-531P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-531P RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RNU6-531P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-531P RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNU6-531P expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

KIRC, HNSC, and LUAD are the cancer types where RNU6-531P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCOSMedianAll0.7320.542<.001108view →
HNSCDFSQuartileIII,IV0.7730.566.00256view →
LUADOSTertileIII,IV0.6150.381.01232view →
UVMDFSQuartileIII,IV0.2620.922.00429view →
MESODFSMedianIII,IV0.2100.626.00427view →
LIHCDFSQuartileAll0.3290.494.00223view →
BRCADFSQuartileIII,IV0.9420.783.00820view →
CESCDFSQuartileAll0.4170.781.00118view →
LAMLDFSQuartileAll0.5190.325.02514view →
DLBCOSTertileAll0.7770.975.03413view →
SKCMDFSQuartileAll0.2560.149.00312view →
UCECOSTertileAll0.8970.940.02910view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RNU6-531P–KIRC (OS)

Kaplan–Meier survival curve for RNU6-531P RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration