RNU6-528P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-528P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-528P data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher RNU6-528P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-528P expression acts as an unfavorable survival marker.

CHOL, PAAD, and THYM are the cancer types where RNU6-528P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CHOLOSTertileAll0.0190.800<.00172view →
PAADOSTertileII,III,IV0.2730.561.01636view →
THYMOSTertileAll0.3520.884<.00124view →
SARCOSTertileAll0.6010.869.00621view →
ESCAOSTertileII,III,IV0.4060.925.03718view →
COADOSTertileIII,IV0.1680.691.04118view →
ACCOSTertileAll0.1460.622.02618view →
BRCAOSTertileAll0.2160.582.01412view →
Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RNU6-528P–CHOL (OS)

Kaplan–Meier survival curve for RNU6-528P RNA-high vs -low samples in CHOL.

Open the CHOL breakdown →

Exploration