RNU6-521P

Across TCGA pan-cancer cohorts, RNU6-521P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-521P data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RNU6-521P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-521P expression acts as an unfavorable survival marker.

LUSC, KICH, and LIHC are the cancer types where RNU6-521P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	II,III,IV	0.208	0.634	.002	108	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
LIHC	OS	Tertile	All	0.089	0.783	<.001	72	view →
KIRP	OS	Tertile	All	0.161	0.904	<.001	72	view →
THCA	OS	Tertile	All	0.916	0.991	.003	39	view →
SARC	OS	Tertile	All	0.155	0.594	.016	18	view →
PCPG	DFS	Tertile	All	0.063	0.924	<.001	18	view →
KIRC	DFS	Tertile	III,IV	0.440	0.662	.040	12	view →
HNSC	DFS	Tertile	II,III,IV	0.415	0.699	.048	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

RNU6-521P–LUSC (OS)

Open the LUSC breakdown →