Across TCGA pan-cancer cohorts, RNU6-520P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-520P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RNU6-520P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-520P is over-expressed in tumor, although a few such as THCA and LIHC show the opposite, repressed pattern.

KICH, THCA, and LIHC are the cancer types where RNU6-520P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-520P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	+0.296	.035	1	view →
THCA	All	All	−0.168	.013	1	view →
LIHC	Female	All	−0.135	.022	1	view →
LUSC	Male	All	−0.134	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNU6-520P RNA expression & survival · all RNU6-520P data types