RNU6-518P

Across TCGA pan-cancer cohorts, RNU6-518P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-518P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU6-518P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-518P expression acts as an unfavorable survival marker, although some lineages such as PAAD show a favorable association.

BLCA, KICH, and HNSC are the cancer types where RNU6-518P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.132	0.720	<.001	126	view →
KICH	DFS	Tertile	All	0.035	0.904	<.001	90	view →
HNSC	OS	Tertile	II,III,IV	0.208	0.674	.006	90	view →
UCEC	OS	Tertile	II,III,IV	0.198	0.768	.002	90	view →
BRCA	OS	Tertile	All	0.210	0.583	<.001	54	view →
PAAD	DFS	Tertile	II,III,IV	1.000	0.266	.028	24	view →
ESCA	OS	Tertile	All	0.565	0.724	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RNU6-518P–BLCA (OS)

Open the BLCA breakdown →