Across TCGA pan-cancer cohorts, RNU6-514P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-514P’s most consistent transcriptional readouts.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where RNU6-514P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-514P is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

PRAD, BRCA, and LUSC are the cancer types where RNU6-514P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-514P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PRAD	All	All	+0.164	.029	2	view →
BRCA	All	III,IV	−0.138	.013	2	view →
LUSC	All	II,III,IV	+0.166	.028	1	view →
KIRC	All	All	+0.090	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNU6-514P RNA expression & survival · all RNU6-514P data types