RNU6-506P

Across TCGA pan-cancer cohorts, RNU6-506P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-506P data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RNU6-506P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-506P expression acts as an unfavorable survival marker, although some lineages such as LGG and SARC show a favorable association.

UCS, ESCA, and BRCA are the cancer types where RNU6-506P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	II,III,IV	0.068	0.631	<.001	108	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	72	view →
BRCA	OS	Tertile	IV	0.106	0.791	<.001	66	view →
STAD	DFS	Tertile	II,III,IV	0.254	0.706	<.001	48	view →
UCEC	DFS	Tertile	All	0.795	0.898	.001	36	view →
BLCA	DFS	Tertile	IV	0.107	0.484	<.001	27	view →
SKCM	DFS	Tertile	III,IV	0.171	0.659	.009	24	view →
LIHC	OS	Tertile	III,IV	0.059	0.738	<.001	18	view →
PCPG	DFS	Tertile	All	0.735	0.947	.005	9	view →
THYM	DFS	Tertile	All	0.318	0.760	.020	6	view →
LGG	OS	Tertile	All	0.668	0.415	.016	3	view →
SARC	OS	Tertile	All	1.000	0.459	.041	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNU6-506P–UCS (OS)

Open the UCS breakdown →