RNU6-505P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-505P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-505P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-505P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-505P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

KIRC, COAD, and KIRP are the cancer types where RNU6-505P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCOSTertileII,III,IV0.1270.806<.001108view →
COADOSTertileAll0.1400.806<.00190view →
KIRPDFSTertileAll0.0380.912<.00166view →
UCECDFSTertileAll0.7190.898.00536view →
THYMDFSTertileAll0.1740.759.02827view →
LUSCDFSTertileAll0.2830.711.01621view →
GBMDFSTertileAll0.0630.297<.00118view →
BLCAOSTertileAll0.1880.687.02018view →
ESCADFSTertileIII,IV0.7690.281.0486view →
SARCOSTertileAll0.5610.841.0206view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

Exploration