RNU6-496P

Across TCGA patient cohorts, RNU6-496P RNA expression is significantly associated with the go_rna of many other GO terms, with 1,642 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-496P-associated GO terms across cancer lineages are Positive regulation of muscle cell apoptotic process, Negative regulation of voltage-gated calcium channel activity, and Regulation of transcription elongation by RNA polymerase II. Each is linked with RNU6-496P in more than 2 cancer types. Because this analysis shows association rather than direction, both RNU6-496P-to-partner and partner-to-RNU6-496P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of muscle cell apoptotic process grouped by RNU6-496P-low versus RNU6-496P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-496P→partner) and Y-score (partner→RNU6-496P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of muscle cell apoptotic process →	+0.110	+0.071	<.001	.006	2	3
STAD	Negative regulation of voltage-gated calcium channel activity →	+0.050	+0.058	.006	.005	3	2
STAD	Regulation of transcription elongation by RNA polymerase II →	+0.142	+0.082	<.001	.004	3	2
STAD	Mismatch repair →	+0.127	+0.083	<.001	.005	3	2
STAD	Water-soluble vitamin metabolic process →	+0.114	+0.059	<.001	.003	3	2
STAD	Interleukin-1-mediated signaling pathway →	+0.129	+0.064	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,642 associations by consensus.

Positive regulation of muscle cell apoptotic process by RNU6-496P expression — STAD

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