RNU6-493P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-493P RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated RNU6-493P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU6-493P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-493P expression acts as an unfavorable survival marker.

BLCA, ESCA, and KIRC are the cancer types where RNU6-493P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCADFSTertileAll0.0830.626<.00172view →
ESCADFSTertileAll0.1480.673.04018view →
KIRCDFSTertileIV0.1660.619.03218view →
BRCAOSTertileII,III,IV0.7400.913.0283view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration