RNU6-492P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-492P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-492P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RNU6-492P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-492P expression acts as an unfavorable survival marker, although some lineages such as STAD and SKCM show a favorable association.

THCA, KIRP, and STAD are the cancer types where RNU6-492P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCADFSTertileAll0.0490.828<.00154view →
KIRPDFSTertileII,III,IV0.0380.783<.00145view →
STADOSTertileIV1.0000.271.01418view →
SARCDFSTertileAll0.1010.611.01318view →
BRCAOSTertileIII,IV0.1400.548.01512view →
UCECDFSTertileAll0.8070.898.0236view →
SKCMDFSTertileAll1.0000.202.0473view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

Exploration