RNU6-489P

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNU6-489P RNA expression is significantly associated with the go_rna of many other GO terms, with 872 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-489P-associated GO terms across cancer lineages are Negative regulation of peptidase activity, Negative regulation of muscle cell apoptotic process, and Striated muscle cell apoptotic process. Each is linked with RNU6-489P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU6-489P-to-partner and partner-to-RNU6-489P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of peptidase activity grouped by RNU6-489P-low versus RNU6-489P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-489P→partner) and Y-score (partner→RNU6-489P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADNegative regulation of peptidase activity →+0.070+0.036.002.00131
STADNegative regulation of muscle cell apoptotic process →+0.063+0.025.002.00131
STADStriated muscle cell apoptotic process →+0.060+0.032.004.00231
STADNegative regulation of striated muscle cell apoptotic process →+0.069+0.024.001.00131
STADRegulation of collagen metabolic process →+0.079+0.026.001.00131
STADPositive regulation of collagen metabolic process →+0.081+0.024.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 872 associations by consensus.

Negative regulation of peptidase activity by RNU6-489P expression — STAD

Box plot of Negative regulation of peptidase activity in RNU6-489P-low vs RNU6-489P-high samples in STAD.

Explore this box plot interactively →

Exploration