RNU6-488P

Across TCGA pan-cancer cohorts, RNU6-488P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-488P data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNU6-488P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-488P expression acts as an unfavorable survival marker.

UCEC, KICH, and SKCM are the cancer types where RNU6-488P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.423	0.841	<.001	108	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
SKCM	OS	Tertile	II,III,IV	0.341	0.742	.012	45	view →
STAD	OS	Tertile	II,III,IV	0.456	0.723	.009	36	view →
KIRC	DFS	Tertile	All	0.128	0.628	.002	36	view →
CESC	DFS	Tertile	All	0.146	0.740	<.001	36	view →
LGG	OS	Tertile	All	0.133	0.811	<.001	36	view →
PCPG	DFS	Tertile	All	0.094	0.768	.008	18	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RNU6-488P–UCEC (DFS)

Open the UCEC breakdown →