RNU6-483P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-483P RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RNU6-483P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU6-483P RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNU6-483P expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

BLCA, COAD, and LIHC are the cancer types where RNU6-483P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCAOSQuartileII,III,IV0.8230.670.00150view →
COADDFSQuartileAll0.6610.830.00428view →
LIHCOSQuartileII,III,IV0.5200.747.00426view →
SKCMOSMedianAll0.8160.750.00425view →
LUADOSMedianAll0.4380.274.00424view →
KIRCDFSMedianIV0.4710.753.00517view →
CHOLOSMedianII,III,IV0.9030.382.00912view →
PRADDFSMedianAll0.8450.924.00312view →
KIRPDFSMedianAll0.9790.796.00810view →
UCECDFSTertileAll0.5590.669.03010view →
GBMOSQuartileAll0.3070.513.0129view →
STADDFSMedianIV0.2400.548.0186view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

Exploration