RNU6-478P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-478P RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated RNU6-478P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU6-478P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-478P expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

BRCA, KIRC, and STAD are the cancer types where RNU6-478P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileAll0.1590.579.01736view →
KIRCOSTertileAll0.2630.636.00530view →
STADOSTertileII,III,IV0.9060.367.03824view →
GBMOSTertileAll0.1090.415.03218view →
PRADOSTertileAll0.7810.990<.00118view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration