RNU6-474P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-474P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-474P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU6-474P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-474P expression acts as an unfavorable survival marker.

BRCA, LIHC, and PAAD are the cancer types where RNU6-474P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileAll0.7650.927<.00190view →
LIHCOSTertileII,III,IV0.1850.722<.00175view →
PAADOSTertileAll0.0600.641<.00172view →
SKCMOSTertileII,III,IV0.2700.745.00127view →
LGGDFSTertileAll0.2360.738.01827view →
KIRCDFSTertileII,III,IV0.1370.503.03518view →
STADDFSTertileIV0.0830.379.0019view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

Exploration