RNU6-469P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-469P RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RNU6-469P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU6-469P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-469P expression acts as an unfavorable survival marker, although some lineages such as LUSC and LUAD show a favorable association.

ACC, ESCA, and CHOL are the cancer types where RNU6-469P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCOSTertileAll0.2920.684<.00187view →
ESCAOSTertileIV0.1270.571.00369view →
CHOLOSTertileIII,IV0.0240.772.00863view →
TGCTDFSTertileAll0.6200.839.00354view →
LUSCOSTertileII,III,IV0.5890.337.00354view →
UCECOSTertileIV0.3490.764.00236view →
READOSTertileII,III,IV0.1780.672.00627view →
BLCADFSTertileAll0.3950.534.02218view →
PAADOSTertileAll0.4350.628.03018view →
DLBCOSTertileIII,IV0.1721.000.01418view →
LUADDFSTertileAll0.8620.769.02712view →
GBMOSTertileAll0.2810.436.0309view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

RNU6-469P–ACC (OS)

Kaplan–Meier survival curve for RNU6-469P RNA-high vs -low samples in ACC.

Open the ACC breakdown →

Exploration