RNU6-454P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-454P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-454P data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNU6-454P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-454P expression acts as an unfavorable survival marker.

UCEC, LUSC, and LIHC are the cancer types where RNU6-454P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSTertileAll0.5820.878<.00190view →
LUSCOSTertileII,III,IV0.1000.780<.00154view →
LIHCDFSTertileAll0.0810.527.01245view →
KIRCDFSTertileII,III,IV0.1940.519.01236view →
OVDFSTertileAll0.3320.545.00936view →
SKCMDFSTertileIV0.0160.454<.00118view →
DLBCDFSTertileAll0.0220.809<.00118view →
STADDFSTertileIV0.0830.379.0019view →
Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

Exploration