RNU6-448P

Across TCGA pan-cancer cohorts, RNU6-448P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-448P data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RNU6-448P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-448P expression acts as an unfavorable survival marker.

LUSC, ESCA, and KIRP are the cancer types where RNU6-448P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	II,III,IV	0.079	0.750	<.001	54	view →
ESCA	OS	Tertile	II,III,IV	0.451	0.706	.008	36	view →
KIRP	OS	Tertile	All	0.485	0.839	.002	21	view →
UCEC	DFS	Tertile	All	0.123	0.648	.008	18	view →
CESC	OS	Tertile	All	0.089	0.585	.025	18	view →
SKCM	DFS	Tertile	All	0.191	0.615	.003	9	view →
BLCA	DFS	Tertile	III,IV	0.214	0.574	.038	9	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RNU6-448P–LUSC (DFS)

Open the LUSC breakdown →