RNU6-445P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-445P RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated RNU6-445P data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RNU6-445P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-445P expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

LUAD, LGG, and CESC are the cancer types where RNU6-445P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSTertileAll0.2060.767.00663view →
LGGOSTertileAll0.0210.896<.00136view →
CESCDFSTertileII,III,IV0.1930.705.04518view →
STADOSTertileIV0.8050.283.03118view →
BLCADFSTertileIII,IV0.1590.572.0369view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RNU6-445P–LUAD (DFS)

Kaplan–Meier survival curve for RNU6-445P RNA-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration