RNU6-440P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-440P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-440P data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RNU6-440P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-440P expression acts as an unfavorable survival marker.

KIRP, BLCA, and ESCA are the cancer types where RNU6-440P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRPOSTertileII,III,IV0.1410.772<.00172view →
BLCAOSTertileIV0.0510.600<.00136view →
ESCAOSTertileAll0.1980.872.00336view →
LUADOSTertileII,III,IV0.2230.749.01336view →
SKCMDFSTertileAll0.0580.757<.00127view →
KIRCDFSTertileIV0.0380.632<.00124view →
CESCDFSTertileII,III,IV0.1460.705.01018view →
PRADOSTertileAll0.5790.883<.00118view →
COADOSTertileAll0.2300.572.02215view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

Exploration