RNU6-437P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-437P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-437P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU6-437P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-437P expression acts as an unfavorable survival marker, although some lineages such as BLCA and OV show a favorable association.

ACC, KIRC, and READ are the cancer types where RNU6-437P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCOSTertileIII,IV0.3530.813<.00196view →
KIRCDFSMedianAll0.4780.733<.00189view →
READOSTertileII,III,IV0.2400.729.00839view →
BLCAOSTertileIII,IV0.5570.311.00237view →
LIHCDFSTertileII,III,IV0.2690.459.00330view →
OVOSMedianII,III,IV0.3670.280.00424view →
KIRPOSTertileII,III,IV0.2060.600.02024view →
THYMOSTertileIV0.2941.000.02518view →
PAADDFSQuartileII,III,IV0.3230.479.02512view →
LUADOSTertileIII,IV0.7020.424.02612view →
UCECDFSTertileIII,IV0.3800.648.02512view →
ESCAOSQuartileAll0.4200.615.0209view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNU6-437P–ACC (OS)

Kaplan–Meier survival curve for RNU6-437P RNA-high vs -low samples in ACC.

Open the ACC breakdown →

Exploration