RNU6-436P

Across TCGA pan-cancer cohorts, RNU6-436P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-436P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RNU6-436P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-436P expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

THCA, THYM, and UCEC are the cancer types where RNU6-436P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	II,III,IV	0.877	0.984	<.001	135	view →
THYM	OS	Tertile	All	0.068	0.977	<.001	72	view →
UCEC	OS	Tertile	IV	0.346	0.764	<.001	54	view →
CESC	DFS	Tertile	II,III,IV	0.270	0.720	.005	54	view →
BRCA	OS	Tertile	All	0.935	0.968	.004	42	view →
LIHC	DFS	Tertile	All	0.214	0.544	.005	42	view →
STAD	OS	Quartile	III,IV	0.312	0.583	.001	33	view →
COAD	OS	Tertile	All	0.523	0.879	<.001	21	view →
BLCA	OS	Tertile	III,IV	0.141	0.581	.011	18	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
KIRC	DFS	Tertile	IV	0.206	0.487	.049	18	view →
LUAD	DFS	Tertile	II,III,IV	0.807	0.648	.035	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNU6-436P–THCA (OS)

Open the THCA breakdown →