Across TCGA pan-cancer cohorts, RNU6-431P RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RNU6-431P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RNU6-431P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-431P expression acts as an unfavorable survival marker, although some lineages such as UCS and LAML show a favorable association.

THCA, COAD, and CHOL are the cancer types where RNU6-431P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.852	1.000	<.001	88	view →
COAD	DFS	Median	All	0.600	0.776	.001	43	view →
CHOL	DFS	Quartile	All	0.196	0.812	.001	30	view →
BLCA	DFS	Quartile	All	0.179	0.473	.016	29	view →
UCS	DFS	Median	IV	0.952	0.367	.001	24	view →
LAML	DFS	Quartile	All	0.743	0.422	.001	24	view →
PCPG	DFS	Tertile	All	0.592	0.873	.001	24	view →
CESC	DFS	Tertile	All	0.389	0.647	.005	22	view →
KIRP	DFS	Median	IV	0.039	0.623	.001	18	view →
PRAD	DFS	Median	All	0.901	0.964	.001	18	view →
LIHC	DFS	Median	All	0.465	0.596	.002	17	view →
SKCM	DFS	Quartile	All	0.262	0.154	.025	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

Exploration

Same gene, other analysis: RNU6-431P tumor-vs-normal RNA expression · all RNU6-431P data types