RNU6-428P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-428P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-428P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU6-428P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-428P expression acts as an unfavorable survival marker.

BRCA, KIRC, and THCA are the cancer types where RNU6-428P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileAll0.6760.925<.00190view →
KIRCDFSTertileIV0.2730.662.00284view →
THCADFSTertileAll0.0490.828<.00154view →
HNSCDFSTertileAll0.2020.631<.00145view →
SKCMDFSTertileAll0.2420.616.00624view →
UCSDFSTertileAll0.1360.523.03418view →
LGGDFSTertileAll0.3740.759.00412view →
GBMOSTertileAll0.2140.415.0419view →
LIHCDFSTertileAll0.1310.544.0229view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

Exploration