RNU6-426P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-426P RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated RNU6-426P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU6-426P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-426P expression acts as an unfavorable survival marker.

HNSC, UCEC, and BRCA are the cancer types where RNU6-426P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSTertileAll0.4130.752<.001129view →
UCECDFSTertileAll0.6140.899.00178view →
BRCADFSTertileAll0.4390.903.01460view →
SARCOSTertileAll0.1620.767.00218view →
STADOSTertileII,III,IV0.2710.720<.00118view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RNU6-426P–HNSC (OS)

Kaplan–Meier survival curve for RNU6-426P RNA-high vs -low samples in HNSC.

Open the HNSC breakdown →

Exploration