RNU6-424P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-424P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-424P data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNU6-424P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-424P expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

UCEC, KIRC, and COAD are the cancer types where RNU6-424P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSTertileAll0.3330.683.00160view →
KIRCOSTertileAll0.3980.639.00460view →
COADOSTertileIII,IV0.0540.783<.00157view →
HNSCOSTertileIII,IV0.0420.682<.00136view →
OVOSTertileIV0.0280.759.00236view →
STADOSTertileII,III,IV0.8260.625.01633view →
LUSCOSTertileAll0.2650.728.00418view →
THCADFSTertileIII,IV0.6990.900.0289view →
Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

Exploration