RNU6-422P

Across TCGA pan-cancer cohorts, RNU6-422P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-422P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-422P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-422P expression acts as an unfavorable survival marker, although some lineages such as BLCA and BRCA show a favorable association.

MESO, BLCA, and BRCA are the cancer types where RNU6-422P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.036	0.563	<.001	108	view →
BLCA	DFS	Tertile	III,IV	0.527	0.248	.012	60	view →
BRCA	DFS	Tertile	All	0.938	0.894	.023	24	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	18	view →
UVM	DFS	Tertile	All	0.213	0.761	.017	18	view →
UCEC	OS	Tertile	IV	0.196	0.513	.048	18	view →
ESCA	OS	Tertile	IV	0.243	0.590	.046	13	view →
LGG	OS	Tertile	All	0.561	0.399	.026	12	view →
ACC	DFS	Tertile	III,IV	0.312	0.727	.002	9	view →
LUSC	OS	Tertile	II,III,IV	0.528	0.801	.025	9	view →
KIRC	DFS	Tertile	All	0.540	0.672	.032	9	view →
PAAD	OS	Tertile	All	0.671	0.279	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNU6-422P–MESO (OS)

Open the MESO breakdown →