RNU6-419P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-419P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-419P data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RNU6-419P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-419P expression acts as an unfavorable survival marker, although some lineages such as ESCA and LUSC show a favorable association.

LIHC, KICH, and TGCT are the cancer types where RNU6-419P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCOSTertileAll0.4080.702<.00187view →
KICHDFSTertileII,III,IV0.0770.851<.00166view →
TGCTDFSTertileII,III,IV0.0880.917.01024view →
MESOOSTertileIV0.0770.592.01918view →
UVMDFSTertileIII,IV0.0790.674.02018view →
ESCADFSMedianII,III,IV1.0000.388.01018view →
COADDFSTertileIII,IV0.1350.616.01918view →
GBMDFSTertileAll0.1500.305.0409view →
LUSCDFSTertileIII,IV0.6460.264.0249view →
READDFSTertileIV0.2550.628.0209view →
SKCMOSTertileAll1.0000.762.0276view →
BLCAOSTertileIII,IV0.7960.552.0326view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNU6-419P–LIHC (OS)

Kaplan–Meier survival curve for RNU6-419P RNA-high vs -low samples in LIHC.

Open the LIHC breakdown →

Exploration