RNA, U6 small nuclear 418, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU6-418P profile across patient tissues and cancer cell-line models. RNU6-418P expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, RNU6-418P is differentially expressed in 10, with the highest sampling consensus in KIRC. Additionally, RNU6-418P RNA expression shows 17,987 significant gene co-expression associations, with the highest sampling consensus in DLBC. Together, these results highlight HNSC, KIRC, and DLBC as cancer lineages where RNU6-418P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU6-418P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU6-418P survival associations across molecular data types. RNU6-418P RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU6-418P RNA expression–survival associations across cancer types. High RNU6-418P expression shows unfavorable associations in ACC and LIHC, but favorable associations in HNSC, BLCA, BRCA and SKCM. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for RNU6-418P RNA expression.
This table summarizes RNU6-418P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for RNU6-418P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-418P shows lower tumor expression in KIRC, KICH, KIRP and BRCA and higher tumor expression in THCA and STAD. The KIRC box plot shows higher RNU6-418P RNA expression in normal versus tumor tissue (log2 FC = −1.201, t-test p < 0.001).
This table shows molecular features associated with RNU6-418P in patient tissues and cancer cell lines. In patient samples, RNU6-418P shows the broadest associations at the RNA and protein expression levels, with DLBC recurring as the lineage with the largest associated feature set.
