RNU6-416P

Across TCGA pan-cancer cohorts, RNU6-416P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-416P data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RNU6-416P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-416P expression acts as an unfavorable survival marker, although some lineages such as LUSC show a favorable association.

UCS, ESCA, and LUAD are the cancer types where RNU6-416P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.222	0.704	.001	72	view →
ESCA	DFS	Tertile	II,III,IV	0.124	1.000	<.001	36	view →
LUAD	OS	Tertile	III,IV	0.068	0.680	<.001	36	view →
THCA	DFS	Tertile	III,IV	0.252	0.760	.021	24	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	18	view →
TGCT	DFS	Tertile	All	0.174	0.801	.041	18	view →
UCEC	OS	Tertile	IV	0.308	0.748	.009	18	view →
READ	DFS	Tertile	III,IV	0.182	0.745	.007	18	view →
LUSC	DFS	Tertile	III,IV	1.000	0.261	.015	12	view →
COAD	DFS	Tertile	All	0.206	0.699	.003	9	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNU6-416P–UCS (OS)

Open the UCS breakdown →