RNA, U6 small nuclear 403, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU6-403P profile across patient tissues and cancer cell-line models. RNU6-403P expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, RNU6-403P is differentially expressed in 11, with the highest sampling consensus in BLCA. Additionally, RNU6-403P RNA expression shows 12,781 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight KIRP, BLCA, and LSCC as cancer lineages where RNU6-403P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU6-403P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU6-403P survival associations across molecular data types. RNU6-403P RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU6-403P RNA expression–survival associations across cancer types. High RNU6-403P expression shows unfavorable associations in KIRP, COAD, PAAD, THCA, KIRC and STAD. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify KIRP as the clearest survival context for RNU6-403P RNA expression.
This table summarizes RNU6-403P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for RNU6-403P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-403P shows lower tumor expression in LUSC and higher tumor expression in BLCA, THCA, COAD, STAD and BRCA. The BLCA box plot shows higher RNU6-403P RNA expression in tumor versus normal tissue (log2 FC = +2.207, t-test p < 0.001).
This table shows molecular features associated with RNU6-403P in patient tissues and cancer cell lines. In patient samples, RNU6-403P shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.